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    How Lupus Affects the Body

    In people with lupus, the immune system begins to recognize and attack the body’s own tissues. This phenomenon is similar to “friendly fire” and causes inflammation in various parts of the body.

    It is important to realize, however, that lupus can affect different people in different ways and that signs and symptoms can come and go, producing periods of flares and remission. The following articles provide an introduction to how lupus may affect different parts of the body.

    • Antiphospholipid Antibodies Antiphospholipis antibodies are antibodies directed against phosphorus-fat components of your cell membranes called phospholipids, certain blood proteins that bind with phospholipids, and the complexes formed when proteins and phospholipids bind.

      Approximately 50% of people with lupus possesses these antibodies, and over a twenty-year period of time, one half of lupus patients with one of these antibodies—the lupus anticoagulant—will experience a blood clot.

    • Arthritis “Arthritis” is a broad term used to describe inflammation of the j

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